Ovalocyte Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Ovalocyte and links to relevant pages within the course.
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| What best describes the cells seen in this illustration: | View Page |
| The red cells in this illustration exhibit which of the following abnormal erythrocyte shapes: | View Page |
| The abnormal RBCs seen in this smear, such as those shown by the arrow are typically seen in: | View Page |
| The abnormal RBC shape seen in this illustration is: | View Page |
| The presence of erythrocytes with altered morphology (as photographed here) has a close association with each of the following conditions except: | View Page |
| The photograph here is of a peripheral smear sent for hematologic review. No clinical information for the patient was sent with the slide. What is the first course of action that the reviewer should take to assist him/her in interpreting the findings on this blood smear? | View Page |
| Hereditary ovalocytosis and elliptocytosis Ovalocytes are rod shaped erythrocytes with nearly parallel lateral walls. If the long axis of an erythrocyte is no more than twice as long as the short axis, the cell is an ovalocyte. If the long axis is more than twice as long as the short axis, the cell is an elliptocyte. Hemoglobin tends to collect at each end of these cells. The ends of the cells are rounded and never pointed, to be differentated from sickle cells. Ovalocytes present in greater than 25% of red cells on the blood smear are characteristic of hereditary ovalocytosis. The oval shape is attributed to a defect in horizontal red cell membrane protein interactions. Lesser numbers of circulating ovalocytes may be present in various anemias including megaloblastic, sideroblastic, iron deficiency, and in thalassemias. A rare ovalocyte (less than 1%) may be found on almost any peripheral blood smear. Resistance to malarial infection may be a beneficial attribute of hereditary ovalocytosis. | View Page |
| Match the following terms with their synonyms. | View Page |
| Schistocytes Two slightly larger fragments can be seen in this slide. One is lower center, and the other is lower right. Two dacryocytes or teardrop cells are seen in the upper center. Several ovalocytes are also present in this field. Schistocytes are seen in the same conditions as keratocytes and have a short survival time in circulation. Schistocytes have somewhat more clinical significance than keratocytes. | View Page |