Osteomyelitis Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Osteomyelitis and links to relevant pages within the course.
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|What is a major complication of toxic shock syndrome related to group A streptococci, leading to 50% mortality?||View Page|
Robinson LG. Kourtis AP.: Tale of a toothpick: Eikenella corrodens osteomyelitis. Infection. 28(5):332-3, 2000 Tale of a Toothpick is a case of Eikenella corrodens osteomyelitis in a young woman, that resulted from puncture of her foot with a toothpick. The epidemiology, microbiology, common clinical presentations and therapy of E. corrodens are reviewed. A brief summary of the extent of toothpick injuries and their infectious complications are also presented.
|We can conclude from Robinson & Kourtis' "Tale of the Toothpick", that, "it is unwise to place a used toothpick in your pocket."||View Page|
Sickle cell anemia can be accompanied by various physical and emotional/mental complications. Physical complications may include: acute chest syndrome blindness cardiomegaly cerebrovascular accident chronic organ damage chronic pain chronic skin ulceration hematuria and renal dysfunction hepatomegaly infections and sepsis nercrosis of bone marrow, bone, and joints osteomyelitis priapism pulmonary arterial hypertension strokeEmotional complications include anxiety and depression. In addition, post-treatment complications that result from repeated transfusions and pharmacotherapy may also occur.
|Clinical significance of Staphylococcus aureus|
In general, the infection that develops is dependent on the virulence of the particular strain, the inoculum size, and immune status of the host. Staphylococcal infections are typically suppurative, producing abscesses filled with pus and damaged leukocytes surrounded by necrotic tissue. Skin infections range from superficial - boils, carbuncles and furuncles, to bullous impetigo; largely opportunistic infections that develop as a result of previous injury e.g., cuts, burns, surgical wounds - and scalded skin syndrome (extensive exfoliative dermatitis; also known as Ritter Disease). Other major infections include pneumonia, osteomyelitis (localized infection of bone), and septic arthritis. S. aureus also causes food poisoning as a result of ingestion of food contaminated with an enterotoxin producing strain (enterotoxins A&D) and the potentially fatal toxic shock syndrome, a multisystem disease most often associated with the use of highly absorbent tampons. Toxic shock syndrome is attributed to another toxin (enterotoxin F – TSST1) released by certain strains of S. aureus.Human staphylococcal infections usually remain localized by the normal host defenses. Foreign objects (fomites) such as sutures or intravenous (IV) lines - are readily colonized by S. aureus from skin and can allow the organism to spread systemically via the blood stream – bacteremia/septicemia - leading to more serious infections. Staphylococcal pneumonia is becoming a frequent complication of influenza. Whatever the mode of entry, the invasive nature of S. aureus always poses the threat of more serious deeper tissue invasion and/or bacteremia and hematogenous spread.
|Heelstick - Neonatal Blood collection|
Microlances (such as the Tenderfoot™ (ITC) or the QuikHeel™ (BD), shown here, are used to puncture the heel & collect capillary blood.These devices control the depth of incision, since going too deep into an infant's heel could injure the heel bone, and cause osteomyelitis (bone infection).