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Nomenclature Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Nomenclature and links to relevant pages within the course.

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CLIA Blood Banking Review
The Rh nomenclature which uses the letters DCE is found in which of the following genetic models:View Page

Fundamentals of Hemostasis
Secondary Hemostasis – The Extrinsic Pathway

The shortest, and least complex of the three pathways, the extrinsic pathway primarily focuses on the interaction of tissue factor with factor VII, leading to the activation of factor VII. Tissue factor, a substance expressed on the surface of cells such as fibroblasts and macrophages found outside the vasculature, initiates coagulation when plasma contained within the vessel walls leaks outside the broken vessel, and comes into contact with these cells. The nomenclature, extrinsic pathway, comes from the fact that tissue factor is external to the vasculature.

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Secondary Hemostasis – The Intrinsic Pathway

Here is where the “cascade” or “waterfall” nomenclature becomes evident as each activated factor triggers the conversion and activation of subsequent factors. Factor XIIa, activated previously, catalyzes the conversion of factor XI into XIa, while in the presence of HMWK. Note: This reaction can occur without HMWK, but will be much slower.

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Normal Peripheral Blood Cells
Definition of a Segmented Cell continued.

Since these recommendations have been adopted by many groups, including the College of American Pathologists and the Centers for Disease Control, we will be using them as our criteria for differentiating between bands and segs.This definition was first reported by the Committee for Clarification of the Nomenclature of Cells and Diseases of the Blood and Blood Forming Organs, in the American Journal of Clinical Pathology (18:443-450, 1948).

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