Morphologic Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Morphologic and links to relevant pages within the course.
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| What is a prominent morphologic feature of lead poisoning: | View Page |
| Which of the following morphologic changes is most characteristic of sickle cell disease? | View Page |
| Which of the following statements are FALSE regarding the bone marrow BIOPSY specimen? | View Page |
| Advantages of a Biopsy Specimen Examining the biopsy allows the structure of the marrow to be viewed as it exists in the body. It provides essential diagnostic information in conditions that disrupt the normal architecture, such as metastatic carcinoma, myelofibrosis, Hodgkin's lymphoma and granuloma. A biopsy may also be used to evaluate cellularity and identify acid-fast bacteria or fungi in less time than is needed for routine culture methods. One disadvantage of the tissue sections prepared from the biopsy sample is that morphologic detail is lost. For this reason, in many cases imprint slides or smears from the aspirated sample are also examined. | View Page |
| Biopsy Touch Preparation A touch prep is made by holding the biopsy plug with a forceps and touching the plug to one or more clean slides in several places. Imprints of the marrow remain on the slide. The slides are quickly air dried, fixed with methanol and stained with Wright-Giemsa or other cytochemical stains. Morphologic details of the cells are preserved with this type of preparation. | View Page |
| Match the name of each fungal species listed with its most likely corresponding morphologic features. | View Page |
| Match the name of each fungal species listed in the drop-down box with its most likely corresponding morphologic feature. | View Page |
| The ability of Candida albicans to alternate between two phenotypes, which may be related to the virulence of this species, is called: | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |
| The presence in the peripheral blood of an increased number of hypersegmented white blood cells as presented in the photograph serves as a marker for preleukemia. | View Page |
| Alder- Reilly Anomaly Large inclusions in leukocyte cytoplasm appear with Alder-Reilly syndrome. Inheritance patterns are not completely clear. The condition is characterized by larger than usual azurophilic and deeply violet staining granules clustered throughout the cytoplasm (even covering the nucleus)in all granulocytes. There are variations in which some lymphocytes and monocytes may be affected. These inclusions represent partially degraded mucopolysaccharides within lysosomes.Alder-Reilly bodies may be found independently of genetic mucopolysaccharidoses as an inherited anomaly (Jordan's anomaly). Cytoplasmic vacuoles of toxic origin are not present in Alder-Reilly cells. The background condition in Alder-Reilly syndrome is mucopolysaccharidosis with various types of bone and cartilage disorders, reported first in gargoylism, then in Hunter and Hurler syndromes. Accompanying conditions are hepatosplenomegaly, corneal opacities, and mental retardation. Reference: Brunning, Richard D. Morphologic Alterations in Nucleated Blood and Marrow Cells in Genetic Disorders. Human Pathol: 99-124, March, 1970 | View Page |
| The peripheral smear photographed here was submitted for morphologic/clinical examination.The predominant cells comprised 70% of the total white blood cells and are consistent with lymphocytes in a 4 month old infant. | View Page |