Morphologic Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Morphologic and links to relevant pages within the course.

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CLIA Hematology / Hemostasis Review
What is a prominent morphologic feature of lead poisoning:	View Page
Which of the following morphologic changes is most characteristic of sickle cell disease?	View Page

Introduction to Bone Marrow
Which of the following statements are FALSE regarding the bone marrow BIOPSY specimen?	View Page
Advantages of a Biopsy Specimen Examining the biopsy allows the structure of the marrow to be viewed as it exists in the body. It provides essential diagnostic information in conditions that disrupt the normal architecture, such as metastatic carcinoma, myelofibrosis, Hodgkin's lymphoma and granuloma. A biopsy may also be used to evaluate cellularity and identify acid-fast bacteria or fungi in less time than is needed for routine culture methods. One disadvantage of the tissue sections prepared from the biopsy sample is that morphologic detail is lost. For this reason, in many cases imprint slides or smears from the aspirated sample are also examined.	View Page
Biopsy Touch Preparation A touch prep is made by holding the biopsy plug with a forceps and touching the plug to one or more clean slides in several places. Imprints of the marrow remain on the slide. The slides are quickly air dried, fixed with methanol and stained with Wright-Giemsa or other cytochemical stains. Morphologic details of the cells are preserved with this type of preparation.	View Page

Mycology: Hyaline and Dematiaceous Fungi
Match the name of each fungal species listed with its most likely corresponding morphologic features.	View Page
Match the name of each fungal species listed in the drop-down box with its most likely corresponding morphologic feature.	View Page

Mycology: Yeasts and Dimorphic Pathogens
The ability of Candida albicans to alternate between two phenotypes, which may be related to the virulence of this species, is called:	View Page

Parasitology Review
Which of the following morphologic forms serve as the diagnostic stage(s) of the amebae:	View Page
Match each parasite listed here with its corresponding infective stage:	View Page
Arrange the following parasites in order according to life cycles from simple to most complex:	View Page
The trophozoite is the only morphologic form in the life cycle of:	View Page
Human infection of the schistosomes occurs following penetration of what morphologic form into the skin?	View Page
Arrange the following Plasmodium morphologic forms in order from immature to mature:	View Page
Which of the following parasites have/has a life cycle that resembles that of the Plasmodium species?	View Page
Recovered in a stool sample, this suspicious form measures 7 µm.	View Page
A 68-year-old female, who recently vacationed in Brazil, presented to her physician exhibiting overall weakness, fever, and enlarged lymph nodes. Blood was collected for culture and parasitic examination. The culture was negative. This suspicious form was recovered upon examining the Giemsa-stained preparation. This patient is most likely suffering from:	View Page
The protozoa are classified and placed in groups based on which of the following criteria?	View Page
Match each parasite name listed below with its corresponding picture:	View Page
Match each parasite with its respective classification:NOTE: Answers may be used more than once.	View Page
Match the parasite pictured with its corresponding name & morphologic form(s):	View Page
Arrange the following parasites in order (smallest to largest) based on relative egg size:	View Page
Match each parasite listed here with the picture of its corresponding egg:Note: Answers may be used more than once.	View Page
Match each parasite listed here with its respective classification:	View Page
Match each parasite listed here with its respective classification:	View Page
Which of the following parasites, whose common names are listed below, is/are intestinal in nature?	View Page
Arrange the parasites listed here in order based on relative size from largest to smallest:	View Page
Which of the following parasites is/are known to contain cytoplasmic ingested red blood cells in the trophozoite morphologic form?	View Page
Label the following morphologic structures on the Giardia lamblia trophozoite pictured here:	View Page
Match each pair of parasites listed here with the key morphologic characteristics that help to distinguish between them:	View Page
Thorn-like pseudopods are characteristic in trophozoite form of:	View Page
Match each parasite listed here with its corresponding key identifying characteristic found in the egg morphologic form:	View Page
Arrange the following morphologic forms based on complexity beginning with the simplest form:	View Page
The morphologic structure of select tapeworms that is most likely responsible for piercing the human intestinal wall is/are called:	View Page
Match each picture with its respective morphologic form:	View Page
Label the morphologic structures on this parasite form:	View Page
Label the morphologic structures on this parasite form:	View Page
Label the morphologic structures on this parasite form:	View Page
Label the morphologic structures on this parasite form:	View Page
Label the morphologic structures on this parasite form:	View Page
Label the morphologic structures on this parasite form:	View Page
Match each parasite morphologic form with its respective key morphologic key characteristic:	View Page
Label the morphologic structures on this parasite form:	View Page
Label the morphologic structures on this parasite form:	View Page
A 44 year old female immigrant from Southeast Asia presented to the local clinic complaining of fever, chills, diarrhea and weakness. Patient history revealed that the woman worked in a research laboratory in her homeland. Her primary project was to develop an effective insecticide for the dreaded sandfly. The doctor decided to culture her blood for parasites. This form, measuring 14 µm, was recovered. The patient is most likely suffering from:	View Page
A fresh stool sample was submitted to the laboratory for parasitic examination on a 30 year old male who presented to a local clinic complaining of gastrointestinal discomfort and overall weakness. The only patient history available about the patient was that he was here job hunting and that he is originally from rural Mississippi. The sample was immediately processed and this suspicious form was seen. No other suspicious forms resembling eggs were seen. The patient is most likely infected with:	View Page
A 27 year old West African immigrant went to the local clinic complaining of fever, chills, and joint pain. The physician immediately ordered blood for parasitic examination. The Giemsa-stained thin blood smear revealed the three suspicious forms below. This patient is most likely suffering from an infection with:	View Page
A 29 year old male steak house owner from Arizona presented to his doctor complaining of weight loss, abdominal pain and diarrhea. Patient history revealed that the man eats all of his meals at his restaurant and his favorite meat is rare sirloin steak. The man also noted that he had recently been on anti-parasitic medication. The doctor ordered a stool for parasitic examination. These two suspicious forms were seen. The patient is most likely suffering from an infection with:	View Page
I am found in stool and measure 33 µm in diameter.	View Page
The developmental morphologic stage in select arthropod life cycles in which the organism physically resembles the corresponding adult stage is called the:	View Page

Semen Analysis

Variations in White Cell Morphology - Granulocytes
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page

White Cell and Platelet Disorders: Peripheral Blood Clues to Nonneoplastic Conditions
The presence in the peripheral blood of an increased number of hypersegmented white blood cells as presented in the photograph serves as a marker for preleukemia.	View Page
Alder- Reilly Anomaly Large inclusions in leukocyte cytoplasm appear with Alder-Reilly syndrome. Inheritance patterns are not completely clear. The condition is characterized by larger than usual azurophilic and deeply violet staining granules clustered throughout the cytoplasm (even covering the nucleus)in all granulocytes. There are variations in which some lymphocytes and monocytes may be affected. These inclusions represent partially degraded mucopolysaccharides within lysosomes.Alder-Reilly bodies may be found independently of genetic mucopolysaccharidoses as an inherited anomaly (Jordan's anomaly). Cytoplasmic vacuoles of toxic origin are not present in Alder-Reilly cells. The background condition in Alder-Reilly syndrome is mucopolysaccharidosis with various types of bone and cartilage disorders, reported first in gargoylism, then in Hunter and Hurler syndromes. Accompanying conditions are hepatosplenomegaly, corneal opacities, and mental retardation. Reference: Brunning, Richard D. Morphologic Alterations in Nucleated Blood and Marrow Cells in Genetic Disorders. Human Pathol: 99-124, March, 1970	View Page
The peripheral smear photographed here was submitted for morphologic/clinical examination.The predominant cells comprised 70% of the total white blood cells and are consistent with lymphocytes in a 4 month old infant.	View Page

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