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Microcytic Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Microcytic and links to relevant pages within the course.

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Laboratories Individuals

Alpha Thalassemia
Wright's stained peripheral blood smear made from EDTA specimen.What RBC morphologies are present?View Page
CBC Results

WBC 6.1 X 10 9/L (Reference range 4.0 - 10.5 X 109/LRBC 4.84 X 1012/L (Reference range 3.50 - 5.50 X 1012/LHb 8.4 g/dL (Reference range 12.0 - 16.0 g/dL)Hct 28.8 % (Reference range 36.0 - 48.0%)MCV 59 fL (Reference range 80.0 - 100.0 fL)MCH 17.4 pg (Reference range 26.0 - 34.0 pg)MCHC 29.3 g/dL (Reference range 32.0 - 36.0 g/dL)RDW 19.5 % (Reference range 11.0 - 15.0 %)Plat 591 X 109/L (Reference range 150 - 400 X 109/L)Even though the RBC count is normal, it is increased for the amount of hemoglobin present. The concentration of hemoglobin in the RBCs is slightly decreased (hypochromic) and the cells are small (microcytic). The variation in RBC size is also slightly increased as are the platelets.

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What is the classification of this patient's anemia, based on the CBC results?View Page

CLIA Hematology / Hemostasis Review
The abnormal RBCs seen in this illustration are indicative of:View Page
The RBCs seen in this illustration are indicative of:View Page
Which of the following would not be represented in the usual classification of anemia:View Page
The reticulocyte count is used to assess which of the following:View Page
Match the disease conditions on the left with appropriate red cell appearances on the right:View Page

Red Cell Disorders: Peripheral Blood Clues to Nonneoplastic Conditions
The condition most likely associated with the peripheral blood picture shown in the photograph is:View Page
The condition most likely associated with the peripheral blood picture in the photograph is:View Page
Dimorphic RBC population

Illustrated in the photomicrograph of a peripheral smear are two populations of erythrocytes. Approximately 50% of the erythrocytes are normal size and contain a full complement of hemoglobin. The patient had received blood transfusions. The transfused red blood cells are the normocytic, normochromic red cells. Admixed are microcytic erythrocytes and larger erythrocytes, some faintly mottled or smudged, suggestive of reticulocytes. This picture represents a hemolytic process with a reticulocyte response. A similar dimorphic red cell population appears following erythropoietin therapy. It is important to recognize when a population of cells in the peripheral smear is not in context with anticipated laboratory findings and the clinical situation.

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Iron Deficiency

Absorption of iron is interrupted in the absence of the stomach. Microcytic, hypochromic red cells are not conspicuous in the previous slides to reflect this deficiency. However, multiple factors influencing red cell morphology are so diverse in this case and therapy so uncontrolled that iron deficiency is not perfectly expressed morphologically.

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Red Cell Morphology
Which of the following terms best describes the cells in this field?View Page


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