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Megakaryocytic Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Megakaryocytic and links to relevant pages within the course.

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Introduction to Bone Marrow
Low Power Magnification

This smear is shown under low power (10x objective) magnification. The reddish cells in the background are mature red blood cells. The dark dots are nucleated erythroid and myeloid precursors. The large dark dot in the middle is a megakaryocyte. Normally, about 5 to 10 megakaryocytes are seen per microscopic field at low power magnification. Clusters of megakaryocytes usually indicate megakaryocytic hyperplasia. Less than 2 megakaryocytes per low power field may mean megakaryocytic hypoplasia.

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High Power Magnification

This field under high magnification shows an increased number of megakaryocytes (megakaryocytic hyperplasia). This patient had thrombotic thrombocytopenic purpura. He was therefore consuming increased numbers of platelets, and his bone marrow was responding by increasing the number of megakaryocytes, which of course break up into platelets.

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