Howell-jolly body Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Howell-jolly body and links to relevant pages within the course.
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| What are Howell-Jolly Bodies? Howell-Jolly bodies are round, smooth, almost pyknotic, dark purple bodies ranging in size from 0.5 to 1.0 micron in diameter. Located eccentrically, usually only one Howell-Jolly body occurs in a mature or nucleated erythrocyte. Occasionally, two or more Howell-Jolly bodies per cell may be found. These DNA inclusions demonstrate a positive Feulgen reaction which is specific for DNA and RNA. | View Page |
| Howell-Jolly Body A Howell-Jolly body is present in a red cell in the center of this field. Notice that the color is deep purple, the shape is round and there is a smooth pyknotic appearance. | View Page |
| Another Howell-Jolly Body The arrows in this image point to additional examples of Howell-Jolly bodies. | View Page |
| Howell-Jolly Body in a Nucleated Red Cell The Howell-Jolly body in this nucleated red cell is right next to the nucleus and not as clearly visible as the one in the preceding slide. | View Page |
| What abnormality is indicated by the arrow on this slide? | View Page |
| What abnormality is present in this slide? | View Page |
| What abnormalities can be seen in this slide? | View Page |
| What abnormalities are present in this slide? | View Page |
| What abnormality is present in this slide? | View Page |
| Howell-Jolly body and Pappenheimer bodies The red cell indicated by the arrow in the center of this field has a single Howell-Jolly body toward the lower left, as well as and several clusters of Pappenheimer bodies. | View Page |
| Howell-Jolly bodies and Pappenheimer bodies This image shows Howell-Jolly bodies, indicated with single arrows, and a cluster of Pappenheimer bodies, indicated with a double arrow. | View Page |
| Comparison of Erythrocyte Inclusions In section A of the image, the arrow points to an RBC with basophilic stippling.In section B, the arrows point to erythrocytes containing Pappenheimer bodies.The arrows are pointing to Howell-Jolly bodies in section C.By contrast, in section D the arrow is pointing to a platelet that is sitting on top of an RBC. This may be mistaken for an inclusion. One of the distinguishing characteristics that can alert you to the fact that it is not an inclusion is the halo around the platelet. | View Page |
| The red cell in the center of the field contains a: | View Page |
| Pappenheimer bodies Pappenheimer bodies are iron-containing granules that aggregate with mitochondria and are deposited in RBC or normoblast cytoplasm. Small and irregular, they are found only in pathological states as thalassemia and sideroblastic anemias(upper image). Wright-Giemsa stain defines the cytoplasmic content (protein), but Prussian blue staining is necessary to define the iron content, the essence of the Pappenheimer body (lower image). Pappenheimer bodies lie typically in small clusters (upper image) and tend to locate at the periphery of the red cell cytoplasm. A cluster is typically smaller than a single Howell-Jolly body. | View Page |
| The cells marked by blue arrows in the photograph are associated with all of the following conditions except: | View Page |