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Hoff Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Hoff and links to relevant pages within the course.

Learn more about laboratory continuing education for medical technologists to earn CE credit for AMT, ASCP, NCA, and state license renewal and recertification. Or get information about laboratory safety and compliance courses that deliver cost-effective OSHA safety training and continuing education to your laboratory's employees.

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Introduction to Bone Marrow
Osteoblast

Another example of a cell rarely seen in the bone marrow is an osteoblast. Osteoblasts are cells which are similar in appearance but somewhat larger than plasma cells or tumor cells. The nucleus is eccentric and the "hoff" area is sometimes located away from the nucleus. The cytoplasm appears rather foamy when compared to a plasma cell. The size of an osteoblast is 20-25 microns. Osteoblast produce bone.

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Plasma Cells

An occasional plasma cell is a normal finding in the bone marrow. The nuclear chromatin pattern is coarse, the cytoplasm is varying shades of blue with a "hoff" or light staining area adjacent to the nucleus.

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White Cell and Platelet Disorders: Peripheral Blood Clues to Nonneoplastic Conditions
The upper image of a peripheral blood smear reveals RBC Rouleaux formation. Several blood cells that are similar in appearance to the one indicated by the arrow in the bottom image are also seen on the smear. Which of the following conditions is associated with both of these findings?View Page


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