Hepatitis Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Hepatitis and links to relevant pages within the course.
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| Clinical Significance Liver damage or an obstructed bile duct allows conjugated bilirubin to enter the circulation and ultimately to appear in the urine. Patients with clinical jaundice due to hepatitis or cirrhosis will have bilirubinuria. If the jaundice is due to red cell destruction, there is an increase in unconjugated bilirubin which the kidneys cannot excrete. | View Page |
| Clinical Significance Urinary urobilinogen may be increased in the presence of a hemolytic process such as hemolytic anemia. It may also be increased with infectious hepatitis, or with cirrhosis. Comparing the urinary bilirubin result with the urobilinogen result may assist in distinguishing between red cell hemolysis, hepatic disease, and biliary obstruction. Urobilinogen is increased in hemolytic disease and urine bilirubin is negative. Urobilinogen is increased in hepatic disease, and urine bilirubin may be positive or negative. Urobilinogen is low with biliary obstruction, and urine bilirubin is positive. Reagent strips methods however, cannot distinguish normal urobilinogen from absent urobilinogen, as might be seen in complete biliary obstruction. | View Page |
| Fresh frozen plasma : | View Page |
| Autologous blood must be tested for which of the following before transfusion: | View Page |
| Increases in blood ammonia levels would be expected in which of the following conditions: | View Page |
| Increases in LD fractions 4 and 5 are indicative of: | View Page |
| Which of the following infectious agents represent the greatest risk to the laboratory worker: | View Page |
| Which one of the following statements about Hepatitis is true? | View Page |
| If greater than 50% lymphocytes were found on the peripheral blood smear of a 5 month old child you would suspect which of the following conditions: | View Page |
| Flow cytometry is not a useful tool in the study of this disorder: | View Page |
| Which one of the following statements about Coxiella burnetii is not true: | View Page |
| Which of the following hepatitis antigens is most directly linked to transmission of HBV: | View Page |
| Match the type of hepatitis with its route of transmission | View Page |
| Match the virus with its disease: | View Page |
| Each of the following is related to the virulence of Listeria monocytogenes except: | View Page |
| Increase Marrow Iron Stores Markely increased stainable iron is present in this biopsy. Iron stores may be increased in sideroblastic anemia, chronic infections, hemochromatosis, hemosiderosis due to numerous blood transfusions, chronic hepatitis, cirrhosis, and uremia. | View Page |
| Assayed and Unassayed Controls Commercially prepared controls come in either assayed or unassayed forms. Assayed controls are tested by multiple methods before sale, and are sold with the results of the tests. Assayed controls: are more expensive than unassayed controls are used to evaluate accuracy and precision avoid laboratory errors in determining control values may only be suitable for specific methods or conditionsWhile the manufacturer's control values can be used to some extent to measure accuracy, the best measure of accuracy is certified reference material.Unassayed controls are not tested by the manufacturer before they are sold. The control values for these materials must be determined by the individual laboratory. Unassayed controls: are less expensive than assayed controls are used to evaluate precision only avoid manufacturer error in determining control values control values are customized to the laboratory's own methods and conditionsA final note: although commercially available control materials are screened for hepatitis antigens and HIV antibodies, control materials should still be handled with precautions, since they contain biological materials and could contain infectious agents. | View Page |
| What happens after HBV infection? After the initial infecting incident, HBV enters an incubation period lasting an average of 60 to 90 days.Following this period is the onset of acute hepatitis, which inflames the liver and causes prolonged illness, often progressing to jaundice.Most infected individuals recover completely, but about 10% get chronic hepatitis, which lasts for years.
Chronic hepatitis may result in cirrhosis or liver cancer. Both are potentially fatal. | View Page |
| Acute hepatitis panel Acute hepatitis panel:
Hepatitis A antibody (IgM)
Hepatitis B core antibody, IgM (HBcAb)
Hepatitis B surface antigen (HBsAg)
Hepatitis C antibody
| View Page |
| The peripheral blood picture is consistent with each of the following conditions except: | View Page |