Hematologic Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Hematologic and links to relevant pages within the course.
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| The tube used for hematologic examinations is: | View Page |
| The most important modifiable risk factor for enteric colonization with vancomycin-resistant Enterococcus faecium is: | View Page |
| Review 3 Kornbluth AA. Danzig JB. Bernstein LH.:
Clostridium septicum infection and associated malignancy. Report of 2 cases and review of the literature.
Medicine. 68(1):30-7, 1989We report 2 patients with myonecrosis due to Clostridium septicum and associated colon carcinoma and have reviewed the English language literature for all reported cases of atraumatic C. septicum infection. A total of 162 cases of C. septicum infection have been reported.Eighty-one percent of these patients had an associated malignancy. Thirty-four percent of all patients had associated colon carcinoma, while 40% had a hematologic malignancy. Thirty-seven percent of reported patients had an occult malignancy at the time of their infection with C. septicum. In many patients, the portal of entry was found in the large intestine.In a particularly lethal form (79% mortality) of C. septicum infection, known as "distant myonecrosis," infection metastatic from the initial site of infection causes severe myonecrosis, gangrene, and often death within hours of clinical detection. Overall, survival of patients with C. septicum infection is only 35%.Review of all cases of C. septicum infection suggests several conclusions. 1) Patients with malignancy, particularly colonic or hematologic, and patients with cyclic neutropenia who develop signs and symptoms of sepsis, especially with associated findings of abdominal pain or pain in an extremity, should be treated for possible clostridial infection. 2) C. septicum infection does not appear to be a result of a single specific defect in either humoral or cell-mediated immunity. Rather, it may occur in patients who are granulocytopenic and therefore prone to an enterocolitis. 3) Patients in whom an infection with C. septicum is found must undergo a vigorous search for malignancy following ac | View Page |
| Each of the following statements is true concerning Clostridium septicum infections except: | View Page |
| Evaluation of Bone Marrow Evaluation of the bone marrow provides both diagnostic and prognostic information for a number of hematologic disorders. Indications for performing a bone marrow include an increase or decrease of any blood cellular element. | View Page |
| Bone marrow examinations may be used to diagnose and monitor a variety of hematologic disorders. | View Page |
| Match the names of each of the fungi listed below into the appropriate category indicating the classification of infection with which it is most commonly associated. | View Page |
| The fungus illustrated in this photomicrograph was recovered from an induced sputum specimen from a 74 year old man with chronic obstructive pulmonary disease. This isolate is most likely: | View Page |
| The peripheral blood smear represented by this field was submitted for hematologic review. The RBC inclusions most likely are: | View Page |
| The photograph here is of a peripheral smear sent for hematologic review. No clinical information for the patient was sent with the slide. What is the first course of action that the reviewer should take to assist him/her in interpreting the findings on this blood smear? | View Page |
| A blood smear represented by the photograph was submitted for hematologic review. Based on the erythrocyte morphology and the accompanying histogram, which of the following choices is the most likely situation or condition? | View Page |
| The arrow on this photomicrograh points to a macrocyte. The oval shape should be noted on the patient report. | View Page |
| The cells included in the composite image were found in a peripheral blood smear with a total WBC of 24,500/mm3. The differential count was:
myelocytes 1
metamyelocytes 4
band neutrophils 15
segmented neutrophils 40
monocytes 8
eosinophils 2
basophils 1
lymphocytes 29.
This hematologic picture is most consistent with: | View Page |
| WBC inclusions: summary The presence of atypical inclusions within the cytoplasm of neutrophils and other leukocytes should lead to a clinical investigation of the setting for these findings.Atypical neutrophil inclusions may be seen in the following disorders: Chediak-Higashi syndrome, May-Hegglin anomaly, Alder-Reilly anomaly, Fechtner , Sebastian, Epstein and Alport-like syndromes and in infectious and toxic conditions (in the form of Doehle bodies).Although a specific entity may not be evident from examination of the peripheral blood alone, it is important that hematology technologists include a comment reporting on the presence of these inclusions or granules. A clinical investigation with further hematologic and genetic studies may then appropriately be considered.Many of the disorders with atypical neutrophil cytoplasmic granules are also associated with platelet abnormalities, particularly giant platelets (lower photograph).Therefore, when atypical granules are recognized, scanning of the peripheral blood smear for atypical platelets may be revealing. These observations serve as readily identifiable markers for acquired and genetic human maladies, and as a guide for unraveling the reasons for a patient's suffering and impaired health. | View Page |