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Granular cast Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Granular cast and links to relevant pages within the course.

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Laboratories Individuals

CLIA Chemistry / Urinalysis Review
What type of cast is shown in the illustration:View Page
Identify the urine sediment elements shown by the arrow:View Page
Identify the urine sediment elements present in this illustration:View Page
Identify the urine sediment elements shown by the arrow:View Page
Identify the urine sediment elements shown by the arrow:View Page
Identify the urine sediment elements shown by the arrow:View Page
Which of the following casts might be found in urine of a healthy individual after strenuous exercise:View Page

CLIA General Laboratory Review
Which of the following casts might be found in the urine of a healthy individual after strenuous exercise:View Page

The Urine Microscopic: Microscopic Analysis of Urine Sediment
Match the following:View Page
The patient was a female and the examination was completed within two hours of collection. Which of the following findings correlate with the presence of a yeast infection of the bladder?View Page
What element is present in this slide?View Page
What element is present in this slide?View Page
Granular Casts

Granular casts are composed of plasma protein aggregates and cellular remnants. Granular casts appear as cylinders of coarse, or fine, highly refractive particles. Coarsely granular casts (yellow arrow) contain large, coarse dark yellow or dark brown granules. They are very irregular in shape as shown in this high power magnification under the brightfield microscope. A hyaline cast can be seen just to the left of the coarse granular cast (blue arrow).

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Coarse Granular Casts

Coarse granular casts lose detail under phase contrast and become more difficult to identify. Conversely, the hyaline cast is distinctly visible under phase contrast. A hyaline case is visible just left of center in this image, and a coarse granular cast is negatively outlined on the left.

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Fine Granular Casts

Fine granular casts contain small refractive granules. These casts appear gray or pale yellow under the brightfield microscope. A phase contrast view is seen here. The presence of an occasional granular cast is not considered pathologic.

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Waxy Casts

Waxy casts appear as cylinders of smooth, highly refractive material. They are yellow, homogeneous and their ends may be square or broken off. Cracks may occur within the cast, giving it a segmented appearance. Waxy casts are believed by some to be the final stage of degeneration of the fine granules of granular casts. Since the granules need time to degrade, this finding implies localized nephron obstruction. Waxy casts are seen in chronic renal failure, and acute and chronic renal allograft rejection. Unusually broad waxy casts are known as renal failure casts. These very broad casts are created in the dilated tubules seen in end-stage renal disease.

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Match the following:View Page


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