Fundamentals of Hemostasis (Online Course)
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Author: Carl T. Swithers, MBA, MT (ASCP), CLS (NCA)
Reviewers: Loretta Moffatt, MHA, MT(ASCP); Leah Coppolino, MPH, CLS(NCA), MT(ASCP)
This course identifies and discusses the aspects of primary and secondary hemostasis. The extrinsic, intrinsic, and common pathways that are part of the coagulation cascade are defined, and the various laboratory tests that are used to evaluate hemostasis are discussed.
Continuing Education Credits
- P.A.C.E.® Contact Hours: 1 hour(s)
- Florida Board of Clinical Laboratory Science CE - General (Hematology): 1 hour(s)
Objectives
- Identify the factors that influence the effectiveness of hemostatic processes.
- Describe the mechanisms that are involved in the arrest of blood flow from a damaged vessel.
- Identify key aspects associated with primary and secondary hemostasis.
- Explain the role of various coagulation components in hemostatic processes.
- Define the extrinsic, intrinsic, and common pathways that are part of the coagulation cascade, identifying the coagulation factors that are associated with each pathway.
- Describe the function of various laboratory tests in evaluating hemostasis.
- Identify common coagulation disorders, their symptomology, and subsequent treatment.
- Explain the role of the prothrombin time and activated partial thromboplastin time in monitoring anticoagulation therapy.
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Course Outline
Click on a link in the outline to view a sample page from this course.
- An Introduction to the Fundamentals of Coagulation
- Primary Hemostasis
- Overview of Secondary Hemostasis
- Overview of Secondary Hemostasis
- Secondary Hemostasis: Fibrin Formation via the Coagulation Cascade
- Consequences Linked to Deficiencies in Coagulation Factors
- What is the ultimate goal of secondary hemostasis?
- Coagulation Factors in the Coagulation Cascade
- Secondary Hemostasis: The Extrinsic Pathway
- Secondary Hemostasis: The Extrinsic Pathway, continued
- Secondary Hemostasis: The Intrinsic Pathway
- Secondary Hemostasis: The Intrinsic Pathway, continued
- Secondary Hemostasis: The Intrinsic Pathway, continued
- Secondary Hemostasis: The Intrinsic Pathway, continued
- Secondary Hemostasis: The Common Pathway
- Secondary Hemostasis: The Common Pathway, continued
- Secondary Hemostasis: The Common Pathway, continued
- Secondary Hemostasis: Coagulation Factor Characteristics
- Factor VII is part of which coagulation pathway?
- The Fibrinolytic System
- The Fibrinolytic System
- The Fibrinolytic System, continued
- Laboratory Tests of Hemostatic Function
- Laboratory Testing of Hemostatic Function
- Collecting Blood Specimens for Coagulation Testing
- Specimen Rejection Criteria
- Prothrombin Time (PT)/INR
- PT/INR, continued
- Activated Partial Thromboplastin Time (aPTT)
- Heparin Anti-Xa Assay
- Which of the following statements is NOT correct?
- Fibrinogen Assay
- Fibrin/Fibrinogen Degradation Products and D-Dimers
- Platelet Function Assay
- Mixing Studies
- Factor Assays
- Which of the following statements regarding D-dimer are true?
- Coagulation Disorders
- Coagulation Disorders
- Coagulation Disorders: Inherited
- Coagulation Disorders: Acquired
- Coagulation Disorders: Platelet Disorders
- Coagulation Disorders and Liver Disease
- Which of the following statements regarding coagulation disorders is correct?
- Anticoagulation Therapy
- Anticoagulation Therapy
- Heparin Therapy
- Oral Anticoagulant Therapy
Additional Information
Level of instruction: Intermediate
Intended Audience: Medical Laboratory Scientists, Medical Technologists and Technicians, Clinical Laboratory Science students, and those interested in reviewing the fundamentals of coagulation.
Author Credentials: Carl T. Swithers, MBA, MT (ASCP), CLS (NCA), is a laboratory examiner with the Pennsylvania Department of Health, specializing in clinical regulatory compliance. A former generalist bench technologist, he also serves as adjunct faculty for an MLT program in Central Pennsylvania.
Reviewer Credentials: Loretta Moffatt, MHA, MT(ASCP), has over 35 years in clinical laboratory science education and serves as the program director for an MT program in North Central Pennsylvania. Leah Coppolino, MPH, CLS(NCA), MT(ASCP) is the Director of the Clinical Laboratory Science Program at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania. She holds a Masters in Public Health from Thomas Jefferson University.
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