Feulgen Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Feulgen and links to relevant pages within the course.
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| What are Howell-Jolly Bodies? Howell-Jolly bodies are round, smooth, almost pyknotic, dark purple bodies ranging in size from 0.5 to 1.0 micron in diameter. Located eccentrically, usually only one Howell-Jolly body occurs in a mature or nucleated erythrocyte. Occasionally, two or more Howell-Jolly bodies per cell may be found. These DNA inclusions demonstrate a positive Feulgen reaction which is specific for DNA and RNA. | View Page |
| What are Cabot rings? Thin, red-violet-staining strands in the shape of rings, figure eights, or shapes of the letter B may on rare occasions be seen in erythrocytes. These structures are called Cabot rings. Although the origin of Cabot rings continues to be illusive, they are not nuclear fragments since they test Feulgen negative. The rings are probably microtubules remaining from a mitotic spindle. Cabot rings have been observed in a few cases of megaloblastic anemia, lead poisoning and other disorders of erythropoiesis, as well as, after a splenectomy. | View Page |