Electron Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Electron and links to relevant pages within the course.
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| Which of the following microscopic techniques is capable of producing a 3-dimensional image : | View Page |
| Which of the following microscopic techniques is best suited for direct examination of the infectious agent of syphilis: | View Page |
| Knizocytes Knizocytes are difficult to find in ordinary smears. They can be described as having a streak of hemoglobin through the center of the cell. This is due to two or more indentations in the cell membrane as seen with the electron microscope. The mechanism for formation is unknown. A knizocyte can be seen in the center of this slide.
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| Poikilocytosis Poikilocytosis is a general term used to describe variations in shape. Practically, however, this term has little meaning since cells varying in shape must be specifically identified to be of diagnostic value to the clinician.The work of the French hematologist, Marcel Bessis, with the scanning electron microscope has significantly increased our understanding of the various unusual shapes erythrocytes may assume and their associated pathophysiology. | View Page |
| Codocyte Target cells are thin-walled cells showing a darkly-stained center area of hemoglobin which has been separated from the peripheral ring of hemoglobin. When viewed under the electron microscope. these cells have a cup-shaped appearance. A codocyte is seen in the center of this slide. | View Page |
| Dohle Bodies Dohle bodies are small blue irregular staining patches of cytoplasm seen near the edge of the cell in granulocytes under certain conditions. Electron microscopic examination reveals that they are composed of aggregates of rough endoplasmic reticulum remaining from an earlier stage of development. | View Page |
| More on May-Hegglin May-Hegglin bodies stain blue and appear to have a more definite shape than Dohle bodies. When examined under electron microscopy, they appear to be aggregates of thread-like structures in a crystal-like arrangement. May-Hegglin inclusions are RNA material believed to be derived from the endoplasmic reticulum.
May-Hegglin bodies can be seen in monocytes and platelets as well as in all mature granulocytes.
The platelets in May-Hegglin anomaly are very bizarre in appearance and thrombocytopenia is usually noted.
When examining a slide that has bizarre platelets and blue-appearing bodies in the cytoplasm, thought should be given to the possibility of the May-Hegglin anomaly. | View Page |