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Drepanocyte Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Drepanocyte and links to relevant pages within the course.

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CLIA Hematology / Hemostasis Review
The abnormal cells seen in this illustration are indicative of:View Page

Red Cell Morphology
Match the forms of poikilocytosis listed below with the physiological/environmental condition associated with their formation from the drop-down box.View Page
Synonym for Depranocytes

The synonym for a drepanocyte is a sickle cell.

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Match the following terms with synonyms:View Page
What type of red cells are indicated by the arrows in this image?View Page
The predominant forms of abnormal morphology seen in this slide are:View Page
Sickle Cell (Drepanocyte)

Sickle cells, also referred to as drepanocytes, are formed as a result of the presence of hemoglobin S in the red cell. As the red cell ages, it becomes rigid as it passes through the low oxygen tension atmosphere of the small capillaries in the body. In the absence of oxygen, hemoglobin S polymerizes into rods, causing the sickle cell shape. The shape of sickle cells can vary from cigar-shaped, as shown in the upper image, to the more severe sickled-form, shown in the bottom image.

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Which of the following forms are frequently artifactual?View Page
Sickle Cell Anemia

Sickle cells can be seen in the peripheral blood of patients who have homozygous sickle cell anemia; however other tests are needed to make the diagnosis. Most sickled cells can revert back to the discoid shape when oxygenated. About 10% of sickled cells are unable to revert back to their original shape after repeated sickling episodes.

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The cell in the center of the field is a/an:View Page


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