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Dehydrogenase Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Dehydrogenase and links to relevant pages within the course.

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Laboratories Individuals

Alpha Thalassemia
Serum Chemistry Results

Test Results Reference Ranges Serum iron 250 g/dL 26 -170 g/dL Iron binding capacity 130 g/dL 250 - 400 g/dL Bilirubin (unconjugated) 2.6 mg/dL 0.2 - 1.0 mg/dL Lactate dehydrogenase 320 U/L 100 - 190 U/L Haptoglobin 52 mg/dL 40 - 330 mg/dL

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Lactate Dehydrogenase

Lactate dehydrogenase is found in the cytoplasm of every cell. LD is present in the serum at a level of 100-190 U/L. The serum LD level will rise during increased cell damage.Persons with alpha thalassemia intermedia usually have an increased levels of lactate dehydrogenase (LD). This LD is of red blood cell origin, which leaks in to the plasma during hemolysis.

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Cerebrospinal Fluid
Which Tests May Be Ordered?

The physician orders tests based on the disorder suspected. For example, CSF may be analyzed for one or more of the following chemical components: sodiumpotassiumchloridemagnesiumproteinglucosecalciumcholesterolcreatininelactic acid dehydrogenase (LDH)phosphorusureauric acid

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Pharmacology in the Clinical Lab: Therapeutic Drug Monitoring and Pharmacogenomics
Enzyme Abnormalities and Drugs

The following is a list of enzymes for which known mutations have been associated with clinical effects. Enzymes Substrates (Drugs) Acetylaldehyde dehydrogenase Alcohol Acetylcholinesterase Succinylcholine Alcohol dehydrogenase Alcohol Dihydropyrimidine dehydrogenase Fluorouracil CYP2C9 Warfarin, phenytoin, losartan CYP2C19 Diazepam, omeprazole (Prilosec) CYP2D6 Many antidepressants, opioids, antiarrhythmics Glucose-6-phosphate dehydrogenase Aspirin, quinidine N-acetyltransferase Procainamide, isoniazid Thioprine methyltransferase 6-mercaptopurine UDP-glucuronosyl transferase Acetaminophen, tolbutamide, irinotecan

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