Cores Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Cores and links to relevant pages within the course.
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Needle biopsies are commonly obtained from the prostate or liver. They will resemble long, thin cores of tissue. Due to the very thin diameter typical of these specimens, it is absolutely essential that they be oriented in the same plane, as flat as possible. It is common for multiple level section protocols to be requested as well as special stains with these specimens, so select the smallest mold that is appropriate for the specimen to make it easier to place multiple sections on the same slide. It is best to arrange the long strings in a parallel arrangement, and not randomly with the long strings facing in many directions. Diagonal arrangement can assist if folds or compression are a problem, since this will reduce the distance that the knife blade travels across the specimen.
Breast cores are similar to other core biopsies, except that a larger bore is used so the cores are often thicker in diameter. Breast cores require special fixation considerations for microscopic and immunohistochemical evaluation.All the submitted cores should be sent for histology processing. Calcifications may be present, and these must be correlated with radiologic findings. These calcifications may present sectioning problems, so when embedding, try to position visible calcifications so that they will cause the least damage to the largest tissue area if this is possible.As with other similar biopsies, embed the cores in parallel rows in one flat plane, rather than in random arrangements in the block face.
|Identify the tissue type shown in the cut surface of this paraffin tissue block.||View Page|