Coombs Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Coombs and links to relevant pages within the course.
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| When AHG or Coombs serum is used to demonstrate that red cells are antibody coated in vivo, the procedure is termed: | View Page |
| What is Coombs sera comprised of: | View Page |
| IgG coated red cells are added to negative antiglobulin tests to detect which of the following sources of error: | View Page |
| Warm antibody hemolytic disease A 49-year-old male with pneumonia was treated with penicillin. He became jaundiced with yellow sclera. Observe the photograph of his peripheral blood smear. Anisocytosis was observed with pale-centered microcytes and polychromatophilic macrocytes. Since penicillin is a classic offender for autoimmune hemolytic disease, the clinician asked for an antihuman globulin (AHG) test, also known as the Coombs test. A positive AHG reaction occurs when the antibody stimulated by penicillin becomes attached to red blood cells. Hemolysis follows, leaving the patient with jaundice and a peripheral blood smear, as demonstrated in the photograph. | View Page |