Chromosomes Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Chromosomes and links to relevant pages within the course.
Learn more about laboratory continuing education for medical technologists to earn CE credit for AMT, ASCP, NCA, and state license renewal and recertification. Or get information about laboratory safety and compliance courses that deliver cost-effective OSHA safety training and continuing education to your laboratory's employees.
| Remnants of erythrocytes nuclei, nuclear fragments, or aggregates of chromosomes which have separated from the mitotic spindle are: | View Page |
| More on Howell-Jolly Bodies Under normal conditions, Howell-Jolly bodies are thought to be remnants of nuclear fragments due to incomplete expulsion of the nucleus. In pathological conditions, they are aggregates of chromosomes which have separated from the mitotic spindle during abnormal mitosis. Single or multiple Howell-Jolly bodies may be found in a red cell. A single HJ body in a red cell may be seen in megaloblastic anemia, hemolytic anemia such as sickle cell anemia and after splenectomy. Megaloblastic anemia or abnormal erythropoiesis is usually present when multiple Howell-Jolly bodies are observed in a single cell. | View Page |
| Infection of the Host Cell (1) The double-stranded DNA molecule now migrates to the nucleus of its host cell. Once it reaches the nucleus, a viral enzyme called integrase joins the replicated HIV DNA to the cell's DNA. The viral DNA now becomes one of the cell's chromosomes and is called a provirus. At this point an individual is infected with and is a carrier of HIV but does not have AIDS. | View Page |
| The ability of Candida albicans to alternate between two phenotypes, which may be related to the virulence of this species, is called: | View Page |
| Barr Body A Barr body appears as a small drumstick-like projection on one of the lobes of a some of the neutrophil in females. Barr bodies are attached to the nuclear lobe by a single narrow stalk which distinguishes them from other thicker projections, sometimes referred to as "clubs." Clubs have a thicker, and sometimes, a double stalk. This projection can be seen in both males and females and has no clinical significance. Barr bodies must also be distinguished from hair-like projections sometimes seen in the band form, following irradiation or in patients with a malignant tumor that has metastasized. Since Barr bodies are the morphological expression of the inactivated X chromosome, one Barr body can be seen in up to 3% of the neutrophils on a female's peripheral blood slide. In rare chromosome disorders in which three or more X chromosomes are present, two to three Barr bodies per neutrophil can be seen. Recognition of a Barr body in a neutrophil is important in order to avoid reporting it as abnormal unless two or more per neutrophil are seen. | View Page |