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Brightfield microscopy Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Brightfield microscopy and links to relevant pages within the course.

Learn more about laboratory continuing education for medical technologists to earn CE credit for AMT, ASCP, NCA, and state license renewal and recertification. Or get information about laboratory safety and compliance courses that deliver cost-effective OSHA safety training and continuing education to your laboratory's employees.

Laboratories Individuals

CLIA General Laboratory Review
Which of the following forms of microscopy is not commonly used in the clinical laboratory:View Page

CLIA Hematology / Hemostasis Review
Which is the best method for examination of synovial crystals:View Page

The Urine Microscopic: Microscopic Analysis of Urine Sediment
Red Cell Cast Under High Power

This slide shows a red cell cast under high power magnification with brightfield microscopy.

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Hyaline Casts

Hyaline casts are the type most commonly seen in the urine sediment. A few hyaline casts may occasionally be found in normal urine, and hyaline casts may be seen after strenuous exercise, during fever, diuretic therapy. Pathologically, hyaline casts may be seen with congestive heart failure, and may be seen together with other types of casts in a variety of renal diseases. Hyaline casts have a refractive index similar to the urine in which they are suspended. For this reason, hyaline casts will appear almost invisible under brightfield microscopy, but are easily of seen by phase-contrast microscopy.

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Renal Tubular Epithelial Cast Under High Power

This slide show a renal tubular epithelial cast under brightfield microscopy.

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Phase-Contrast Microscopy

Phase contrast is used to detect casts and mucus which have a very low refractive index and may be missed using brightfield microscopy. Phase contrast enhances the outlines of casts and mucus, making their detection much easier.

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Red Cells Under Brightfield Microscopy and High Power Magnification

Under brightfield microscopy and high power magnification, red cells appear as pale green or orange discs about 7 microns in diameter.

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Squamous Epithelial Cells

The most common type of cell seen in the urine sediment is the epithelial cell. This slide shows squamous epithelial cells under low power brightfield microscopy. They appear as large flattened cells with abundant cytoplasm and small round central nucleus. Although squamous epithelial cells have little clinical significance they must be differentiated from other cellular elements.

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Which of the following are characteristic of normal RBCs under high power (40x) brightfield microscopy?View Page
All of the following are characteristic of WBCs under high power (40x) brightfield microscopy except that they:View Page
Mucous Threads

Mucous threads are semi-transparent under brightfield microscopy and could be mistaken for hyaline casts. They occur as ribbon-like strands with poorly defined edges, pointed or split ends and longitudinal striations.

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