| Nuclear changes include: | View Page |
| A patient has a WBC count of 4,000/mm3, platelet estimation is 3 bizarre platelets/oil immersion field, hemoglobin, hematocrit, red cell count and indice values are within normal limits. Blue staining inclusions are seen in the cytoplasm of many neutrophils. These inclusions fit the description of: | View Page |
| Auer rods are seen in the cytoplasm of: | View Page |
| What morphological change is present in this slide? | View Page |
| What morphological change is present in this slide? | View Page |
| What morphological change is present in this slide? | View Page |
| What morphological change is present in this slide? | View Page |
| What morphological change is present in this slide? | View Page |
| Two Blasts Two blasts are seen in this field. The lower one contains an Auer rod in the cytoplasm near 7 o'clock. It is similar to the one that the technologist saw when she was examining Monica McMurray's slide.
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| Which of the following inclusions have a similar appearance on a Wright's stained smear? | View Page |
| The inclusions that can be of diagnostic significance when seen in the cytoplasm of myeloblasts are: | View Page |
| Match each of the following. Answers may be used more than once or not at all. | View Page |
| Auer rods are significant when they are seen in the cytoplasm of blast cells because they are diagnostic for: | View Page |
| Chediak-Higashi is characterized by: | View Page |
| Alder-Reilly is characterized by: | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |
| Auer Rods Auer rods are red staining, needle-like bodies seen in the cytoplasm of myeloblasts, and/or progranulocytes in leukemia.
Auer rods are cytoplasmic inclusions which result from an abnormal fusion of the primary (azurophilic) granules. Single or multiple Auer rods may be seen in the cytoplasm of a cell. If more than one is present, they are frequently close together and may even be overlapping.
Their identification is very important because, if found, they can confirm the presence of myeloblasts indicating the presence of a myeloid (non-lymphoblastic) leukemia. They can also be seen in myeloid blast crisis in chronic granulocytic leukemia. Auer rods are never seen in lymphoblasts. This differentiation is important because the treatment of lymphoblastic and myeloblastic leukemia are different.
Auer Rods always classified as pathological. | View Page |
| Two Auer Rods Several Auer rods can be seen in the cytoplasm of this cell at approximately 12 o'clock. | View Page |
| One Auer Rod One Auer rod can be seen in the cytoplasm of this cell at approximately 11 o'clock.
Auer rods are easily missed. When many blasts are present on a slide, you should look for them carefully. | View Page |
| Which morphologic term describes this slide? | View Page |
| The inclusions that are frequently seen on the same slide with toxic granulation include: (Choose ALL of the correct answers) | View Page |
| Which morphologic term describes this slide? | View Page |
| Which morphologic term describes this slide? | View Page |