Auer rod Information and Courses from MediaLab, Inc.

These are the MediaLab courses that cover Auer rod and links to relevant pages within the course.

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Cerebrospinal Fluid

Blast Cells

Blast cells may be seen in the spinal fluid when cell proliferation in acute leukemia or lymphoma spreads to the central nervous system. The arrows indicate the two blasts in this field. Notice the smooth chromatin pattern in the nucleus and prominent nucleoli in both cells. Notice that an Auer rod is present in the cytoplasm in the blast to the right. The Auer rod indicates that these blasts are myeloblasts rather than lymphoblasts. A segmented neutrophil and several red cells can also be seen.

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CLIA Hematology / Hemostasis Review
Identify the object contained in the cell in this illustration indicated by the arrow:	View Page
Identify the object contained in the cell in this illustration indicated by the arrow:	View Page

Variations in White Cell Morphology - Granulocytes
Nuclear changes include:	View Page
A patient has a WBC count of 4,000/mm3, platelet estimation is 3 bizarre platelets/oil immersion field, hemoglobin, hematocrit, red cell count and indice values are within normal limits. Blue staining inclusions are seen in the cytoplasm of many neutrophils. These inclusions fit the description of:	View Page
Auer rods are seen in the cytoplasm of:	View Page
What morphological change is present in this slide?	View Page
What morphological change is present in this slide?	View Page
What morphological change is present in this slide?	View Page
What morphological change is present in this slide?	View Page
What morphological change is present in this slide?	View Page
Two Blasts Two blasts are seen in this field. The lower one contains an Auer rod in the cytoplasm near 7 o'clock. It is similar to the one that the technologist saw when she was examining Monica McMurray's slide.	View Page
Which of the following inclusions have a similar appearance on a Wright's stained smear?	View Page
The inclusions that can be of diagnostic significance when seen in the cytoplasm of myeloblasts are:	View Page
Match each of the following. Answers may be used more than once or not at all.	View Page
Auer rods are significant when they are seen in the cytoplasm of blast cells because they are diagnostic for:	View Page
Chediak-Higashi is characterized by:	View Page
Alder-Reilly is characterized by:	View Page
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page
Auer Rods Auer rods are red staining, needle-like bodies seen in the cytoplasm of myeloblasts, and/or progranulocytes in leukemia. Auer rods are cytoplasmic inclusions which result from an abnormal fusion of the primary (azurophilic) granules. Single or multiple Auer rods may be seen in the cytoplasm of a cell. If more than one is present, they are frequently close together and may even be overlapping. Their identification is very important because, if found, they can confirm the presence of myeloblasts indicating the presence of a myeloid (non-lymphoblastic) leukemia. They can also be seen in myeloid blast crisis in chronic granulocytic leukemia. Auer rods are never seen in lymphoblasts. This differentiation is important because the treatment of lymphoblastic and myeloblastic leukemia are different. Auer Rods always classified as pathological.	View Page
Two Auer Rods Several Auer rods can be seen in the cytoplasm of this cell at approximately 12 o'clock.	View Page
One Auer Rod One Auer rod can be seen in the cytoplasm of this cell at approximately 11 o'clock. Auer rods are easily missed. When many blasts are present on a slide, you should look for them carefully.	View Page
Which morphologic term describes this slide?	View Page
The inclusions that are frequently seen on the same slide with toxic granulation include: (Choose ALL of the correct answers)	View Page
Which morphologic term describes this slide?	View Page
Which morphologic term describes this slide?	View Page

White Cell and Platelet Disorders: Peripheral Blood Clues to Nonneoplastic Conditions
Auer Rod Illustrated in the photograph is a immature granulocyte with a distinct rod-shaped intracytoplasmic inclusion. This inclusion is known as an Auer rod, which is seen in up to 10% of blast cells in patients with acute myelogenous leukemia. An Auer red is the fusion of primary granules into rod-like inclusions.	View Page
The cell illustrated in the photograph is known as a faggot cell.	View Page
The cytoplasmic inclusion illustrated at the tip of the blue arrow is characteristic of:	View Page