Anti-e Information and Courses from MediaLab, Inc.
These are the MediaLab courses that cover Anti-e and links to relevant pages within the course.
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| Immune Antibodies Immune antibodies occur in the serum of individuals who become sensitized to foreign antigens through pregnancy or transfusion. IgM predominates in the primary response, IgG in the secondary response. Most react at 37°C and are considered clinically significant. Examples include antibodies in the Kell, Rh, Duffy, and Kidd systems. Immune antibodies can be classified as alloantibodies or autoantibodies.Alloantibodies Produced by exposure to foreign red cell antigens which are non-self antigens but are of the same species. They react only with allogenic cells. Exposure occurs through pregnancy or transfusion. Examples include anti-K and anti-E. Autoantibodies Produced in an autoimmune process and directed against one's own red cell antigens. React with patient's own cells and all cells tested. Can possibly mask the presence of other significant antibodies. It is very important to make sure that no underlying significant antibodies are present if an autoantibody is suspected. A positive direct antiglobulin test (DAT) or auto control could indicate the presence of an autoantibody. Examples include cold auto (P or I) or warm auto (Rh specificity). | View Page |
| If an R1 r patient received R2R2 blood, which of these antibodies could be produced : | View Page |
| If an Rh negative patient is administered a unit of R1R1 packed red cells, which one of the following antibodies would be most likely to develop: | View Page |
| Which of the following antibodies is the most common cause of hemolytic disease of the newborn: | View Page |
| Using the guidelines in the Antibody Exclusion Protocol, which antibodies are possible (have not been excluded) using this panel? Select all that apply.Antibody identification results CellRhRhesusKellDuffyKiddMNSsPLewisLuResultsCell CDEceCwKkKpaFyaFybJkaJkbMNSsP1LeaLebLuaGel IAT* 1rr000++00+0+0+00++++S+001+1 2rr000++00+0+0++0++++S+00w+2 3rr000++00+0++0+0++0+0+003 4r"r00+++00+0++0+0+0+++0004 5R2R20+++00+00+++++0+0+0+0w+5 6 | | View Page |
| Which of the following cells would be the one most useful cell to exclude both anti-E and anti-K in this patient? | View Page |